Immunological Studies on human Serum Lipoprotein

Immunological and Biochemical Studies on Serum Haptoglobin

Antibody to purified type 1-1 human serum haptoglobin was obtained in rabbits. Using this antiserum it was demonstrated that the antigenic determinants of the haptoglobin molecule reside in both alpha- and beta-chains. No immunological difference between the normal alpha(1F)- and alpha(1S)-chains of haptoglobin could be detected. A number of healthy individuals whose haptoglobin pattern appeare...

Electrophoretic studies on human serum.

Archibald, R. M. (1944). J. biol. Chem. 154, 643. Coulson, R. A., Ellinger, P. & Holden, M. (1944). Biochem. J. 38, 150. Ellinger, P. (1946a). Biochem. J. 40, xxxi. Ellinger, P. (1946b). Biochem. J. 40, xxxii. Ellinger, P. & Coulson, R. A. (1944). Biochem. J. 38, 265. Ellinger, P., Fraenkel, G. & Abdel Kader, M. M. (1947). Biochem. J. 41, 559. Johnson, B. C. (1945). J. biol. Chem. 159, 227. Kon...

On the structure of human serum high-density lipoprotein: studies by the technique of circular dichroism.

Previous studies from this laboratory employing the technique of optical rotatory dispersion (ORD) have shown that human serum high-density lipoprotein (HDL) of d 1.063-1.21 gm/ml has a high content in a-helix which is to a large extent retained in its lipid-free form, apo HDL.1 On the basis of the ORD parameters, an unordered structure was assigned to the nonhelical portion of the apoprotein, ...

[Immunological studies on cryoglobulin].

Activation of lipoprotein lipase by lipoprotein fractions of human serum.

Triglycerides in fat emulsions are hydrolyzed by lipoprotein lipase only when they are "activated" by serum lipoproteins. The contribution of different lipoprotein fractions to hydrolysis of triglycerides in soybean oil emulsion was assessed by determining the quantity of lipoprotein fraction required to give half-maximal hydrolysis. Most of the activator property of whole serum from normolipid...